Influence of Second-Trimester Ultrasound Markers for Down Syndrome in Pregnant Women of Advanced Maternal Age

Table 4

Odds ratios for the ultrasound markers for Down syndrome.

Marker		Down syndrome		Odds ratio	Confidence interval (95%)
		Absent	Present
Nuchal fold thickness ≥ 6 mm	Present	35	12	14.9	6.7–33.0
	Absent	823	19
Intracardiac hyperechogenic focus	Present	35	4	3.5	1.1–10.5
	Absent	823	27
Short femur length	Present	2	1	14.2	1.3–161.7
	Absent	856	30
Structural fetal malformation	Present	26	6	7.7	2.9–20.3
	Absent	832	25