Clinical Study

Perinatal Risks Associated with Early Vanishing Twin Syndrome following Transfer of Cleavage- or Blastocyst-Stage Embryos

Table 3

Comparison of perinatal outcomes in patients undergoing cleavage-stage ETs () or blastocyst-stage ETs () with early VT.

ParameterCleavage-stage ()Blastocyst-stage ()OR (95% CI)

Age (years)38.1 (±2.98)36.2 (±1.01)<0.001
Number of embryos transferred2.64 (±0.91)1.69 (±0.42)<0.001
Implantation rate39.7%43.2%0.83 (0.47–1.46)0.52
Mode of delivery0.87
 Vaginal378 (53.3%)38 (54.3%)0.96 (0.59–1.57)
 Cesarean331 (46.7%)32 (45.7%)
Term birth639 (90.1%)64 (91.4%)0.86 (0.33–2.23)0.75
Preterm birth0.70
 Late preterm41 (5.78%)4 (5.71%)0.71 (0.12–4.12)
 Early preterm29 (4.09%)2 (2.86%)
Overall birth weight (g)3187.1 (±409.9)3198.2 (±387.2)0.82
LBW79 (11.1%)8 (11.4%)0.97 (0.40–2.33)0.95
VLBW8 (1.13%)1 (1.43%)0.79 (0.07–9.43)0.85
Term LBW30 (4.69%)4 (6.25%)0.74 (0.22–2.53)0.63

Data are presented as mean ± standard deviation, median (interquartile range), and (%); LBW: low birth weight; VLBW: very low birth weight; OR: odds ratio; CI: confidence interval.