Perinatal Risks Associated with Early Vanishing Twin Syndrome following Transfer of Cleavage- or Blastocyst-Stage Embryos
Table 3
Comparison of perinatal outcomes in patients undergoing cleavage-stage ETs () or blastocyst-stage ETs () with early VT.
Parameter
Cleavage-stage ()
Blastocyst-stage ()
OR (95% CI)
Age (years)
38.1 (±2.98)
36.2 (±1.01)
—
<0.001
Number of embryos transferred
2.64 (±0.91)
1.69 (±0.42)
—
<0.001
Implantation rate
39.7%
43.2%
0.83 (0.47–1.46)
0.52
Mode of delivery
0.87
Vaginal
378 (53.3%)
38 (54.3%)
0.96 (0.59–1.57)
Cesarean
331 (46.7%)
32 (45.7%)
Term birth
639 (90.1%)
64 (91.4%)
0.86 (0.33–2.23)
0.75
Preterm birth
0.70
Late preterm
41 (5.78%)
4 (5.71%)
0.71 (0.12–4.12)
Early preterm
29 (4.09%)
2 (2.86%)
Overall birth weight (g)
3187.1 (±409.9)
3198.2 (±387.2)
—
0.82
LBW
79 (11.1%)
8 (11.4%)
0.97 (0.40–2.33)
0.95
VLBW
8 (1.13%)
1 (1.43%)
0.79 (0.07–9.43)
0.85
Term LBW
30 (4.69%)
4 (6.25%)
0.74 (0.22–2.53)
0.63
Data are presented as mean ± standard deviation, median (interquartile range), and (%); LBW: low birth weight; VLBW: very low birth weight; OR: odds ratio; CI: confidence interval.