Research Article

Placental Vitamin D-Binding Protein Expression in Human Idiopathic Fetal Growth Restriction

Table 1

Clinical inclusion criteria for FGR.

Patient characteristicsFGR-affected ()

Fetal birthweight
 <10th centile18 (100%)
 <3rd centile11 (61%)

Fetal growth pattern (HC : AC ratio)
 Asymmetrical (≥1.2)10 (56%)
 Symmetrical (<1.2)8 (44%)

Amniotic fluid index
 Abnormal (≤7)9 (50%)
 Normal (>7)9 (50%)

Umbilical artery Doppler
 Abnormal (S : D ratio > 95th percentile or absent EDF)8 (44%)
 Normal (S : D ratio < 95th percentile)10 (56%)

Fetal growth trajectory
 Significantly impaired (≥30% drop during the third trimester)2 (11%)
 Adequate (<30% deviation)16 (89%)

Maternal factors
 Gestational diabetes1 (6%)
 Preeclampsia1 (6%)
 Chronic hypertension1 (6%)
 Smoking5 (28%)
 Alcohol abuse1 (6%)

HC : AC: head circumference : abdominal circumference ratio.
S : D: systolic : diastolic ratio.
EDF: end-diastolic flow.
Patients may fulfil more than one category.