Schizophrenia: A Pathogenetic Autoimmune Disease Caused by Viruses and Pathogens and Dependent on Genes

Table 2

Pathogens expressing proteins with homology to the autoantigens reported in schizophrenia. The size of the tags is proportional the number of pathogen’s proteins that are homologous to the autoantigen. Note that the profile is different for each pathogen. The original BLAST files can be found at http://www.polygenicpathways.co.uk/blasts.htm.

Autoantigen reference	Pathogens
CHRNA7 Nicotinic cholinergic receptor [89]
CHRM1 Muscarinic cholinergic receptor [90]
DRD2 Dopamine receptor [82]
GRIN1 NMDA receptor subunit [91]
ELANE Leukocyte elastase [92]
OPRM1 Opioid receptor [93]
NGF Nerve growth factor [92]
HTR1A Serotonin receptor [93]
HSP60 Heat shock protein 60 [94]
HSPA12A Heat shock protein 70 [95]
HSP90 Heat shock protein 90 [95]
PAM/MYC [94]
S100B [96]
STRN Striatin [96]