In Vivo Antimalarial Activity of Annona muricata Leaf Extract in Mice Infected with Plasmodium berghei

Table 1

Effect of A. muricata aqueous leaf extract on parasitemia and mean survival time.

Treatment	Dose (mg/kg)	% parasitemia	% inhibition	Mean survival time
A. muricata	100	34.02 ± 1.5	38.03	18.32 ± 0.84
	500	13.59 ± 1.8	75.25	24.79 ± 1.76
	1000	7.9 ± 0.2	85.61	28.75 ± 1.37
Chloroquine	10	0.52 ± 0.05	99.05	30.33 ± 1.61
Distilled water	1 mL	54.9 ± 4.39	0	7.79 ± 0.73

⁢, , and , compared to untreated control. Parasitemia and mean survival time were expressed as mean ± SEM, . Chloroquine: positive control; distilled water: untreated control.