Antimalarial Activity of Kaempferol and Its Combination with Chloroquine in Plasmodium berghei Infection in Mice

Table 1

Chronic oral toxicity of kaempferol in mice.

Parameter	Control (10 ml/kg of DW)	2,000 mg/kg of KMF
Liver function test
AST (U/L)	39.07 ± 0.42	35.23 ± 0.72
ALT (U/L)	13.75 ± 0.32	13.25 ± 0.22
Renal function test
BUN (mg/dl)	45.55 ± 7.12	40.42 ± 2.34
Creatinine (mg/dl)	1.74 ± 0.31	1.57 ± 0.82
Complete blood cells
Erythrocyte count (cells/mm3)	6.13x10^6 ± 5.43 x 10^5	6.23x10^6 ± 5.23x10^5
Leucocyte count (cell/mm3)	1,618 ± 43.21	1,621 ± 25.67
Neutrophils (%)	35.45 ± 0.61	37.74 ± 0.85
Eosinophils (%)	2.14 ± 0.58	3.25 ± 0.45
Basophils (%)	4.10 ± 0.36	4.01 ± 0.55
Monocytes (%)	6.99 ± 0.35	6.56 ± 0.24
Lymphocytes (%)	56.00 ± 1.47	56.67 ± 2.47