Research Article

Investigating the Role of Mucin as Frontline Defense of Mucosal Surfaces against Mycobacterium avium Subsp. hominissuis

Table 1

Binding of bacteria to the MUC2 mucin.

BacteriaAdherence to MUC2 mucin at different concentrations
0.1 (%)1 (%)5 (%)

M. avium 104000
M. avium 3388000
E. coli49.5 ± 0.651.0 ± 1.244.3 ± 0.8
P. aeruginosa94.1 ± 0.492.6 ± 0.597.3 ± 0.3
S. aureus000
L. monocytogenes95.0 ± 0.296.2 ± 0.497.5 ± 0.2

Bacteria were prepared as described in Section 2. Agar/mucin and mucin control were used. The numbers represent the subtraction of adherence from the background (agar alone). The adherence of E. coli, P. aeruginosa, and L. monocytogenes was statistically significant compared to that of M. avium and S. aureus ().