Plantago ovata F. Mucilage-Alginate Mucoadhesive Beads for Controlled Release of Glibenclamide: Development, Optimization, and In Vitro-In Vivo Evaluation

Table 5

Results of curve fitting of the in vitro glibenclamide release data from different IHM-alginate mucoadhesive beads.

Formulation codes	Correlation coefficient (𝑅^2)				Release exponent (𝑛)
	Zero-order	First-order	Higuchi	Korsmeyer-Peppas
F-1	0.997	0.900	0.552	0.992	1.094
F-2	0.997	0.892	0.590	0.994	1.055
F-3	0.996	0.902	0.607	0.991	1.025
F-4	0.995	0.915	0.533	0.994	1.103
F-5	0.992	0.832	0.599	0.985	1.084
F-6	0.998	0.910	0.586	0.991	1.037
F-7	0.996	0.912	0.527	0.992	1.115
F-8	0.986	0.898	0.560	0.992	1.086
F-9	0.998	0.906	0.548	0.990	1.100
F-O	0.997	0.902	0.530	0.994	1.108