Cellular Redox Status Regulates Emodin-Induced Radiosensitization of Nasopharyngeal Carcinoma Cells In Vitro and In Vivo

Figure 6

Changes in HIF-1α protein expression in CNE-1 cells treated with radiation alone or radiation combined with emodin. Group A (control cells), group B (cells cultured under hypoxic conditions), group C (cells treated with 3.9 mg/L emodin only), group D (cells treated with 2 Gy only), group E (cells treated with 3.9 mg/L emodin under hypoxic conditions), group F (cells treated with 2 Gy under hypoxic conditions), group G (cells treated with 3.9 mg/L emodin and 2 Gy), and group H (cells treated with 3.9 mg/L emodin and 2 Gy under hypoxic conditions).