Dissolution Enhancement of Rosuvastatin Calcium by Liquisolid Compact Technique

Table 4

Physical parameter of liquisolid tablet.

Liquisolid system	Hardness (kg/cm^2)	Thickness (mm)	Disintegration time (sec)	Friability (%)	Weight variation (mg)	Content uniformity (%)
LS-1	3.82±0.28	3.4±0.02	14±0.28	0.21	241.8±1.1	99.25±0.24
LS-2	4.20±0.42	3.0±0.01	16±0.51	0.30	253.4±0.8	98.25±0.20
LS-3	4.62±0.31	2.9±0.01	18±0.50	0.45	341.5±1.8	98.00±0.51
LS-4	3.91±0.14	3.4±0.02	17±0.32	0.33	272.1±1.2	96.51±0.44
LS-5	4.42±0.31	3.2±0.04	22±0.40	0.45	368.4±1.6	97.26±0.23
LS-6	4.71±0.15	3.0±0.02	26±0.14	0.53	483.1±0.4	98.60±0.45
LS-7	4.15±0.18	3.7±0.01	19±0.21	0.29	332.5±1.0	98.21±0.50
LS-8	4.54±0.35	3.4±0.03	24±0.53	0.37	492.2±0.7	95.27±0.15
LS-9	4.62±0.23	2.9±0.01	28±0.42	0.34	638.1±1.5	97.51±0.25
DCT	4.80±0.22	3.5±0.01	44±0.15	0.48	248.4±0.5	99.00±0.42