Research Article
Innovative Approach for Interstitial Cystitis: Vaginal Pessaries Loaded Diazepam—A Preliminary Study
Table 2
Parameters of formulation process in manufacturing and storage phase.
| Set-up phase | Parameters evaluation |
| | Temperature of about 75°C guarantees a complete fusion of all excipients and absence of aggregates | Manufacturing | Sonication avoids air bubbles formation (Figure 2(a)) contributing to obtain a homogenous dispersion of diazepam powder into fused matrix | | Mould filling has been performed by analytical balance in order to uniform mass content at about 3.6 grams | Storage | Pessaries must not be exposed to solar light and they must be stored at 4°C in order to preserve diazepam activity |
|
|