Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design
Table 10
Analysis of variance (ANOVA) for all two responses.
% Release at 2 hour
% Release at 8 hour
Source
Source
F-value
P value
F-value
P value
Model
344.65
0.0409
Model
272.39
0.004
Linear mixture
389.03
0.0358
Linear mixture
162.92
0.0003
AB
490.78
0.0287
AB
56.11
0.0003
BC
58.17
0.0830
AC
23.94
0.0005
ABC
741.53
0.0234
19.97
0.0006
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