Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design

Table 10

Analysis of variance (ANOVA) for all two responses.

	% Release at 2 hour			% Release at 8 hour
Source			Source
	F-value	P value		F-value	P value
Model	344.65	0.0409	Model	272.39	0.004
Linear mixture	389.03	0.0358	Linear mixture	162.92	0.0003
AB	490.78	0.0287	AB	56.11	0.0003
BC	58.17	0.0830	AC	23.94	0.0005
ABC	741.53	0.0234	𝐵1	19.97	0.0006