Journal of Pharmaceutics / 2013 / Article / Tab 10

Research Article

Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design

Table 10

Analysis of variance (ANOVA) for all two responses.

% Release at 2 hour% Release at 8 hour
SourceSource
F-valueP valueF-valueP value

Model344.650.0409Model272.390.004
Linear mixture389.030.0358Linear mixture162.920.0003
AB 490.780.0287AB 56.110.0003
BC 58.170.0830AC 23.940.0005
ABC 741.530.0234 19.970.0006

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