Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design

Table 12

Trial batch formulations of plain xyloglucan and carboxymethyl xyloglucan.

Ingredients	Formulations
	𝑀1	𝑀2
Tramadol HCl	100	100
TSP	150	—
CM-TSP	—	150
DCP	20	20
Talc	5	5
Magnesium stearate	5	5
PVP K-30	30	30
Isopropyl alcohol	qs.	qs.
Total	310	310