Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design

Table 2

Dissolution model for formulations from 𝐴₁ to 𝐴₅.

Batch code	Release exponent (n)	Kinetic constant (K)	R	Best fit model
𝐴1	0.6948	32.71	0.9692	Matrix
𝐴2	0.7634	28.67	0.9736	Matrix
𝐴3	0.7791	25.36	0.9795	Matrix
𝐴4	0.8372	19.82	0.9817	Matrix
𝐴5	0.6834	15.26	0.9854	Matrix

Non-Fickian.