Research Article
Preparation and Evaluation of Valsartan Liquid Filling Formulations for Soft Gels
Table 1
Liquid filling formulations of VAL.
| | Ingredients (mg/cap) | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 |
| | Valsartan | 40 | 40 | 40 | 40 | 40 | 40 | 40 | 40 | 40 | 40 | 40 | | PVP K 30 | — | — | — | — | 10 | 10 | 20 | — | 10 | 10 | 20 | | PEG 400 | 100 | 100 | 160 | 130 | 120 | 120 | 110 | 130 | 120 | 120 | 110 | | PG | 40 | 20 | — | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | | BHT | — | — | — | — | — | — | — | — | — | 1.0 | 1.0 | | SBS | — | — | — | — | — | 0.1 | 0.1 | — | — | — | — | | Water | 20 | 40 | — | 20 | 20 | 20 | 20 | — | — | — | — | | Ethanol | — | — | — | — | — | — | — | 20 | 20 | 20 | 20 |
| | Total weight | 200 | 200 | 200 | 200 | 200 | 200 | 200 | 200 | 200 | 200 | 200 |
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PVP K 30: polyvinylpyrrolidone; PEG 400: polyethylene glycol; PG: propylene glycol; BHT: butylated hydroxy toluene; SBS: sodium meta bisulfite.
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