Solubility Enhancement of Raloxifene Using Inclusion Complexes and Cogrinding Method

Table 3

Optimization ratio of RLX with guar gum and modified guar gum. All values are mean ± S.D, 𝑛 = 3.

Ratio	Concentration (mg/mL)
	RLX-GG	RLX-MGG
1 : 1	1.11 ± 0.041*	0.87 ± 0.065*
1 : 2	1.33 ± 0.005*	1.09 ± 0.004*
1 : 3	1.40 ± 0.109*	1.11 ± 0.010*
1 : 4	1.46 ± 0.017*	2.13 ± 0.011*
1 : 5	1.63 ± 0.012*	2.30 ± 0.031*
1 : 6	2.01 ± 0.015*	2.41 ± 0.013*
1 : 7	2.18 ± 0.056*	3.54 ± 0.011*
1 : 8	2.32 ± 0.015*	3.69 ± 0.012*
1 : 9	2.35 ± 0.007	3.67 ± 0.023

*Significant (𝑃 value < 0.05).