Journal of Pharmaceutics / 2013 / Article / Tab 5

Research Article

Solubility Enhancement of Raloxifene Using Inclusion Complexes and Cogrinding Method

Table 5

Dissolution efficiency of RLX, RLX-HPβCD inclusion complex, and RLX-MGG cogrind mixture. All values are mean ± S.D, = 3.

SampleDissolution efficiency
DE60DE120

Raloxifene28.92 ± 1.98*41.41 ± 2.04
RLX-HPβCD inclusion complex83.34 ± 1.14*84.47 ± 0.84*
RLX-MGG cogrind mixture49.70 ± 1.18*51.30 ± 1.57*

*Significant ( value < 0.05).

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