Development of Orodispersible Tablets of Candesartan Cilexetil-β-cyclodextrin Complex

Table 3

Precompression parameters of prepared granules (F₁ to F₁₂).

Formulation code	Bulk density^a (g/mL)	Tapped density^a (g/mL)	Hausner’s ratio^a	Carr’s index^a (%)	Angle of repose^a (θ)
F1	0.41±0.002	0.61±0.002	1.51±0.002	33.31±0.11	18^∘26^′±0.115
F2	0.41±0.002	0.49±0.002	1.25±0.002	16.72±0.15	22^∘58^′±0.642
F3	0.38±0.002	0.54±0.002	1.44±0.002	30.64±0.20	26^∘56^′±0.550
F4	0.41±0.002	0.62±0.002	1.50±0.002	33.35±0.11	25^∘64^′±1.155
F5	0.36±0.002	0.51±0.002	1.40±0.01	28.61±0.10	30^∘11^′±0.818
F6	0.36±0.002	0.46±0.002	1.27±0.01	21.53±0.05	18^∘26^′±0.346
F7	0.41±0.002	0.55±0.002	1.33±0.011	25.04±0.15	27^∘92^′±1.601
F8	0.42±0.002	0.63±0.002	1.52±0.02	33.33±0.20	22^∘78^′±4.215
F9	0.42±0.002	0.56±0.002	1.33±0.01	25.08±0.15	26^∘56^′±1.172
F10	0.38±0.002	0.55±0.002	1.44±0.01	30.72±0.15	27^∘47^′±0.692
F11	0.41±0.002	0.54±0.002	1.33±0.01	24.91±0.05	23^∘74^′±0.642
F12	0.41±0.002	0.62±0.002	1.50±0.01	33.37±0.15	22^∘78^′±0.692

aMean ± S.D (𝑛=3).