Development of Orodispersible Tablets of Candesartan Cilexetil-β-cyclodextrin Complex

Table 5

Postcompression parameters for prepared orodispersible tablets.

Formulation code	Weight variation^a (mg)	Friability^a (%)	Hardness^a (kg/cm^2)	Percentage drug content^a
F1	140±2.58	0.66±0.01	5.1±0.12	99.4±0.68
F2	150±2.65	0.67±0.01	5.1±0.05	99.8±1.00
F3	150±1.10	0.67±0.01	5.2±0.11	100.15±1.00
F4	150±2.58	0.66±0.01	4.6±0.11	98.66±1.15
F5	150±2.58	0.66±0.01	5.2±0.12	98.14±1.15
F6	140±2.66	0.67±0.01	4.8±0.05	99.71±2.11
F7	154±2.47	0.66±0.05	5.5±0.11	99.9±0.92
F8	140±2.70	0.66±0.01	5.4±0.05	100.15±1.66
F9	156±2.10	0.66±0.02	5.2±0.05	99.52±1.15
F10	155±4.10	0.67±0.01	5.4±0.01	100.28±1.61
F11	157±2.10	0.66±0.05	4.2±0.11	100.1±0.69
F12	140±4.10	0.66±0.01	5.4±0.01	98.66±1.61
F13	150±2.10	0.67±0.05	4.7±0.11	99.04±1.61
F14	150±2.45	0.66±0.05	5.3±0.16	99.23±1.61
F15	140±2.45	0.67±0.01	5.3±0.16	99.33±1.89
F16	150±2.67	0.66±0.01	5.8±0.19	99.71±1.67
F17	158±2.10	0.67±0.01	5.4±0.01	99.9±1.61
F18	140±4.10	0.66±0.05	4.8±0.11	100.3±1.61
F19	150±2.10	0.67±0.01	5.5±0.01	100.09±1.89
F20	150±2.45	0.66±0.05	4.8±0.11	100.28±1.67
F21	140±2.45	0.67±0.05	5.6±0.16	99.9±1.15
F22	150±2.67	0.66±0.01	5.2±0.16	99.71±1.61
F23	150±2.10	0.66±0.01	5.8±0.19	99.61±0.69
F24	150±2.45	0.67±0.05	5.1±0.19	99.52±1.15

aMean ± S.D (𝑛=3).