Research Article
Development of Orodispersible Tablets of Candesartan Cilexetil-β-cyclodextrin Complex
Table 7
IR spectral studies.
| Sample | Wave number (cm−1) | Observation |
| Candesartan cilexetil | 3083.38 | C–H aromatic stretch | 3335.62 | N–H secondary stretch | 1718.26 | C=O stretch | 1248.86 | C–N stretch and CH3 rock |
| -Cyclodextrin | 3612.12 | –OH groups | 2934.34 | CH2 stretch | 1205.21 | Asymmetric C–O–C stretch |
| Inclusion complexes prepared by kneading method | 3321.65 | N–H secondary stretch | 3645.24 | –OH groups | 1710.34 | C=O stretch |
| Inclusion complexes prepared by lyophilisation | 3346.87 | N–H secondary stretch | 1705.46 | C=O stretch | 2921.41 | CH2 stretch |
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