Research Article

Development of Orodispersible Tablets of Candesartan Cilexetil-β-cyclodextrin Complex

Table 7

IR spectral studies.

SampleWave number (cm−1)Observation

Candesartan cilexetil3083.38C–H aromatic stretch
3335.62N–H secondary stretch
1718.26C=O stretch
1248.86C–N stretch and CH3 rock

-Cyclodextrin3612.12–OH groups
2934.34CH2 stretch
1205.21Asymmetric C–O–C stretch

Inclusion complexes prepared by kneading method 3321.65N–H secondary stretch
3645.24–OH groups
1710.34C=O stretch

Inclusion complexes prepared by lyophilisation3346.87N–H secondary stretch
1705.46C=O stretch
2921.41CH2 stretch