Study on Mixed Solvency Concept in Formulation Development of Aqueous Injection of Poorly Water Soluble Drug

<div class="floats-full-page floats-full-page-other"><h2>Table 7</h2><div class="floats-full-page-caption">Chemical stability data of formulation F8.</div><div class="floats-full-page-content"><table class="table-group" id="tab7"><tr><td><table class="table"><tr><td class="thead-hr" colspan="7"><hr /></td></tr><tr class="thead"><td align="left" rowspan="2">Formulation code</td><td align="center" rowspan="2">Temperature</td><td align="center" colspan="4">Concentration* mg/vials</td><td align="center" rowspan="1">&#13;
										Degradation</td></tr><tr class="thead"><td align="center">0 day</td><td align="center">7 day</td><td align="center">15 day</td><td align="center">30 day</td></tr><tr><td class="thead-hr" colspan="7"><hr /></td></tr><tr><td align="left"> </td><td align="center">4 ± 2°C</td><td align="center">80.04 ± 0.012</td><td align="center">79.41 ± 0.013 </td><td align="center">79.03 ± 0.011</td><td align="center">79.06 ± 0.014</td><td align="center">1.18%</td></tr><tr><td align="left">F8</td><td align="center">37 ± 2°C</td><td align="center">80.04 ± 0.012</td><td align="center">79.22 ± 0.011</td><td align="center">78.94 ± 0.014</td><td align="center">78.87 ± 0.020</td><td align="center">1.42%</td></tr><tr><td align="left"> </td><td align="center">60 ± 2°C</td><td align="center">80.04 ± 0.009</td><td align="center">78.84 ± 0.021</td><td align="center">78.47 ± 0.019</td><td align="center">78.59 ± 0.012</td><td align="center">1.77%</td></tr><tr class="table-tr"><td colspan="7"><hr class="tbody-hr" /></td></tr></table></td></tr><tr class="table-fn"><td><svg height="13.75" id="M11" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.5625 13.75" width="10.5625" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.012,-0,0,-.012,2.9,5.525)"><path d="M471 153q-22 -15 -61 -13q-25 31 -45.5 49.5t-56.5 41.5q4 -71 28 -134q-17 -33 -42 -46q-24 12 -42 46q24 63 28 134q-36 -23 -56.5 -41.5t-45.5 -49.5q-36 -2 -61 13q0 28 19 59q65 10 130 43q-65 33 -130 43q-19 31 -19 59q22 15 61 13q25 -31 45.5 -49.5t56.5 -41.5&#10;q-4 71 -28 134q17 33 42 46q24 -12 42 -46q-24 -63 -28 -134q36 23 56.5 41.5t45.5 49.5q36 2 61 -13q0 -28 -19 -59q-65 -10 -130 -43q65 -33 130 -43q19 -31 19 -59z" id="x2217"></path></g>
</svg>Average of 3 determinations.<br /></td></tr></table></div></div>

Table 7 | Study on Mixed Solvency Concept in Formulation Development of Aqueous Injection of Poorly Water Soluble Drug

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Table 7: Study on Mixed Solvency Concept in Formulation Development of Aqueous Injection of Poorly Water Soluble Drug

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Table 7

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