Synthesis, Characterization, and Anti-Inflammatory Activity of Newer Quinazolinone Analogs

Table 1

Anti-inflammatory and analgesic data of compounds 5–22 .

Comp. number	Dose; (mg/kg p.o.)	Anti-inflammatory activity % oedema inhibition	Analgesic activity %
5	50	15.1	11.6
6	50	21.8	16.2
7	50	16.7	14.9
8	50	18.2	17.1
9	50	24.1	19.3
10	50	20.4	18.5
11	50	18.3	14.6
12	50	24.6	18.7
13	50	20.8	16.2
14	50	22.4	20.6
15	50	27.3	25.8
16	50	26.1	22.2
17	50	22.9	16.3
18	50	26.3	19.8
19	50	24.5	22.4
20	50	27.1	25.1
21	50	32.5	29.6
22	50	29.8	28.3
Phenylbutazone	50	38.8	36.5