Journal of Pharmaceutics

Research Article

Dissolution Rate Enhancement, Design and Development of Buccal Drug Delivery of Darifenacin Hydroxypropyl β-Cyclodextrin Inclusion Complexes

Table 9

Vapour transmission rate of prepared mucoadhesive buccal patches.
Formulation codeMoisture vapour transmission (g cm−2 h−1)
Day 1Day 3Day 7
Hb15.32 × 10−3  ± 0.23 × 10−32.24 × 10−3  ± 0.26 × 10−30.93 × 10−3  ± 0.39 × 10−3
Hb27.54 × 10−3  ± 2.32 × 10−32.14 × 10−3  ± 0.81 × 10−31.63 × 10−3  ± 0.56 × 10−3
Hb37.44 × 10−3  ± 0.44 × 10−32.70 × 10−3  ± 0.53 × 10−30.83 × 10−3  ± 0.07 × 10−3
Hb48.81 × 10−3  ± 1.82 × 10−33.87 × 10−3  ± 0.72 × 10−31.22 × 10−3  ± 0.72 × 10−3
Hb59.42 × 10−3  ± 2.32 × 10−33.77 × 10−3  ± 0.87 × 10−31.33 × 10−3  ± 0.46 × 10−3
Pb15.76 × 10−3  ± 0.62 × 10−32.18 × 10−3  ± 0.17 × 10−31.33 × 10−3  ± 0.08 × 10−3
Pb26.88 × 10−3  ± 1.45 × 10−32.65 × 10−3  ± 0.81 × 10−31.50 × 10−3  ± 0.36 × 10−3
Pb37.32 × 10−3  ± 1.23 × 10−32.68 × 10−3  ± 0.47 × 10−30.78 × 10−3  ± 0.22 × 10−3
Pb48.47 × 10−3  ± 0.80 × 10−33.89 × 10−3  ± 0.46 × 10−31.53 × 10−3  ± 0.55 × 10−3
Pb58.35 × 10−3  ± 0.93 × 10−33.91 × 10−3  ± 0.98 × 10−30.90 × 10−3  ± 0.50 × 10−3