Table 4: Cumulative amount permeated, flux, and permeability coefficient of SRP across excised rat skin.

FormulationCumulative amount permeated (μg/cm2)Mean flux (μg/cm2·hr)Permeability coefficient (cm2/hr) × 103Enhancement ratio

SRP solution in Tris-buffer
SRP niosomal dispersion 2.32
SRP niosomal gel without DMSO 0.14
SRP niosomal gel with DMSO 0.69