Development and Evaluation of Mouth Dissolving Films of Amlodipine Besylate for Enhanced Therapeutic Efficacy

Table 1

Composition of different MDFs containing AMLO.

Ingredients (mg)	Formulae (5 g size)
	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12
AMLO	100	100	100	100	100	100	100	100	100	100	100	100
HPMC E3	375	375	375	—	—	—	—	—	—	—	—	—
HPMC E5	—	—	—	375	375	375	—	—	—	—	—	—
HPMC E15	—	—	—	—	—	—	375	375	375	—	—	—
MC	—	—	—	—	—	—	—	—	—	100	100	100
PEG 400	25	25	25	25	25	25	25	25	25	25	25	25
SLS	—	2	—	—	2	—	—	2	—	—	2	—
PVP	—	—	2	—	—	2	—	—	2	—	—	2
Water	1730	1728	1728	1730	1728	1728	1730	1728	1728	1780	1778	1778
Methanol	2750	2750	2750	2750	2750	2750	2750	2750	2750	2950	2950	2950
Pineapple flavor	10	10	10	10	10	10	10	10	10	10	10	10
Aspartame	10	10	10	10	10	10	10	10	10	10	10	10