Research Article

Fast Disintegrating Combination Tablet of Taste Masked Levocetrizine Dihydrochloride and Montelukast Sodium: Formulation Design, Development, and Characterization

Table 13

Determination of drug contents by different methods.

FormulationDispersion time (sec.)Drug content (%) by dilution methodDrug content (%) by Petri dish method
Levocetrizine dihydrochlorideMontelukastLevocetrizine dihydrochlorideMontelukast

K131.41 ± 0.4194.65 ± 1.0893.53 ± 1.1596.02 ± 1.2695.14 ± 1.14
K230.15 ± 0.5396.38 ± 1.1394.17 ± 1.0695.28 ± 1.2393.04 ± 1.19
K326.32 ± 0.6496.68 ± 1.0593.88 ± 0.9897.41 ± 1.1994 .53 ± 1.26
K419.79 ± 0.5998.14 ± 0.9795.63 ± 0.9298.74 ± 1.1695.78 ± 1.16
K522.62 ± 0.4797.46 ± 1.1694.05 ± 1.0298.10 ± 1.2493.92 ± 1.28
K624.58 ± 0.6898.22 ± 1.1492.98 ± 1.1396.68 ± 1.1895.11 ± 1.17