Fast Disintegrating Combination Tablet of Taste Masked Levocetrizine Dihydrochloride and Montelukast Sodium: Formulation Design, Development, and Characterization

Table 14

Determination of disintegration time by different methods.

Formulation	Disintegration by disintegration apparatus (sec.)	Disintegration Time in the Oral Cavity (DT).	Disintegration by Petri dish method (sec.)	Disintegration by dissolution apparatus with basket (sec.)
K1	23 ± 0.76	24 ± 0.16	31 ± 0.89	28 ± 0.43
K2	20 ± 0.63	26 ± 0.24	32 ± 0.72	29 ± 0.51
K3	19 ± 0.58	22 ± 0.19	30 ± 0.94	26 ± 0.47
K4	16 ± 0.55	21 ± 0.25	21 ± 0.67	20 ± 0.39
K5	16 ± 0.61	22 ± 0.21	23 ± 0.74	21 ± 0.44
K6	20 ± 0.51	24 ± 0.18	26 ± 0.69	24 ± 0.53