Fast Disintegrating Combination Tablet of Taste Masked Levocetrizine Dihydrochloride and Montelukast Sodium: Formulation Design, Development, and Characterization

Table 18

Dissolution profile of stability study batch K4.

% Cumulative drug release in phosphate buffer (pH 6.8)—Kyron-T-104 (SSG + CP)
Month batch →	0		1		2		3
Time (min) ↓	L	M	L	M	L	M	L	M
5	24.43	21.38	25.62	19.38	26.51	25.43	25.23	23.10
10	43.57	34.79	43.37	34.89	42.78	37.92	43.42	40.25
15	63.13	43.62	58.82	52.66	61.48	51.07	59.68	52.31
20	81.68	64.91	81.36	66.23	82.39	66.61	81.91	66.47
25	94.86	82.41	93.71	81.56	95.72	82.39	93.86	80.54
30		93.06		91.49		91.98		91.23

L: Levocetrizine dihydrochloride; M: Montelukast sodium.