Development and Evaluation of Taste Masked Granular Formulation of Satranidazole by Melt Granulation Technique

Table 7

% cumulative release and assay in 0.1 N HCL.

Time (minutes)	F1	F2	F3	F4	Marketed formulation
5	7.61±0.367	8.02±0.512	8.71±0.426	5.31±0.378	9.34±0.432
10	86.93±0.523	52.99±0.69	33.9±0.299	25.71±0.362	28.87±0.471
15	98.46±0.647	62.68±0.489	46.05±0.343	36.12±0.298	39.1±0.572
30	104.34±0.701	73.40±0.397	65.83±0.378	58.54±0.452	65.43±0.503
45	102.17±0.489	81.66±0.434	78.57±0.418	71.27±0.514	83.66±0.66
60	102.11±0.585	90.01±0.546	87.65±0.404	76.87±0.539	88.1±0.55
Assay (%)	100.87±0.465	98.91±0.487	99.69±0.574	101.25±0.521	97.89±0.464

∗All above readings are average ± standard deviation, 𝑛=6.