Review Article

Lipid-Based Drug Delivery Systems

Table 4

Some of the commercially available lipid-based formulations.

Molecules/trade nameIndicationDoseType of formulationLipid excipients and surfactants

Calcitriol/RocaltrolCalcium regulatorAdult: 0.25–0.5  g q.d.Soft gelatin capsuleFractionated triglyceride of coconut oil
Cyclosporin/NerolImmunosuppressant2–10 mg/kg/day b.i.d.Soft gelatin capsuleCremophor RH 40
Tretinoin/VesanoidAntineoplastic 45 mg/m2 subdividedSoft gelatin capsuleBees wax, hydrogenated soybean oil
Valporic acid/DepakeneAntiepileptic10–60 mg/kg/daySoft gelatin capsuleCorn oil
Fenofibrate/FenogalAntihyperlipoproteinemic200 mg q.dHard gelatin capsuleGelucire
Testosterone/RestandolHormone replacement therapy40–160 mg q.d.Soft gelatin capsuleOleic acid