Research Article

Formulation and Evaluation of Multilayered Tablets of Pioglitazone Hydrochloride and Metformin Hydrochloride

Table 3

Characteristic peaks of FTIR graphs.

Bond and frequency (cm−1)Pure drugsOptimized multilayer tablet formulated with guar gum (cm−1)
Metformin (cm−1)Pioglitazone (cm−1)

N–H (1°) 
3400–3250
3368.233373.61

N–H (2°)
3400–3250
3148.153282.95

C=N
1471–1689
1559.801566.25

C=O
1760–1665
1741.901674.27

C–O
1000–1300
1242.841244.13

C–S
600–700
659.27682.82

C=N
1471–1689
1509.531533.46