Research Article

Surface Deposition and Coalescence and Coacervation Phase Separation Methods: In Vitro Study and Compatibility Analysis of Eudragit RS30D, Eudragit RL30D, and Carbopol-PLA Loaded Metronidazole Microspheres

Table 2

Correlation coefficient () of different formulations of metronidazole microspheres using different polymers by coacervation and coalescence methods, respectively.

Formulation codeZero orderFirst orderHiguchi modelKorsmeyer model

F250.97210.97730.96820.979515.710.8405
F260.97160.98050.96590.993514.320.8543
F270.94830.97560.95730.989113.880.879
F280.94940.96330.98090.98422.700.7253
F290.98550.98110.96420.997116.720.7488