Enhancement of Solubility of Lamotrigine by Solid Dispersion and Development of Orally Disintegrating Tablets Using 3² Full Factorial Design

Table 2

Drug content and solubility of solid dispersions.

Formulation number	% drug content	Solubility (mg/mL)
Pure drug	—	0.16 ± 0.001
LP1	98.3 ± 1.221	0.40 ± 0.013
LP2	98.7 ± 1.880	0.55 ± 0.003
LP3	99.1 ± 1.551	0.83 ± 0.003
LB1	99.9 ± 1.550	0.52 ± 0.002
LB2	98.4 ± 1.253	0.61 ± 0.001
LB3	97.8 ± 1.503	0.77 ± 0.001