Journal of Pharmaceutics / 2016 / Article / Tab 3

Research Article

Freeze Dried Quetiapine-Nicotinamide Binary Solid Dispersions: A New Strategy for Improving Physicochemical Properties and Ex Vivo Diffusion

Table 3

Results of equilibrium solubility of QF coamorphous dispersions compared to pure QF.

FormulaHPLC peak areaAverage concentration (mcg/mL ± SD)Number of folds’ increase in solubility% Increase in solubility (% ± SD)Theoretical drug content/5 mg dispersionActual drug content/5 mg dispersion

F15694755.973.92
F25786286.073.92
F396369010.093.22
F47929338.313.22
F5134176314.032.73
F6139883314.632.73
928681.000.005.00

.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.