Formulation and Evaluation of Antibacterial Creams and Gels Containing Metal Ions for Topical Application

Table 6

Antimicrobial activity during the stability study.

Product	Type of storage container	Testing period	Zone of inhibition (mm) (mean ± SD)
			Temperature
			4°C	25°C
C1	Plastic jar	Day 1	22.7 ± 0.4	23.9 ± 0.2
		Week 3	23.4 ± 0.6	22.4 ± 0.7
		Week 6	23.1 ± 0.4	22.2 ± 0.5
		Week 9	22.8 ± 0.5	21.4 ± 0.1
		Week 12	22.1 ± 0.3	21.7 ± 0.4
	Glass jar	Day 1	23.6 ± 0.1	24.1 ± 0.8
		Week 3	21.9 ± 0.2	21.9 ± 0.2
		Week 6	22.1 ± 0.2	21.7 ± 0.5
		Week 9	22.1 ± 0.5	21.6 ± 0.3
		Week 12	21.9 ± 0.2	21.2 ± 0.2
G1	Plastic jar	Day 1	25.3 ± 0.3	24.8 ± 0.4
		Week 3	25.5 ± 0.4	25.0 ± 0.2
		Week 6	24.2 ± 0.3	24.2 ± 0.6
		Week 9	25.5 ± 0.4	25.6 ± 0.5
		Week 12	24.3 ± 0.6	25.1 ± 0.1
	Glass jar	Day 1	25.3 ± 0.3	24.7 ± 0.7
		Week 3	25.6 ± 0.3	25.1 ± 0.2
		Week 6	24.1 ± 0.3	24.2 ± 0.2
		Week 9	25.2 ± 0.3	25.7 ± 0.2
		Week 12	24.4 ± 0.2	24.7 ± 0.4
Control (gentamicin)		22.4 ± 0.8