Research Article

Cellulose Acetate 398-10 Asymmetric Membrane Capsules for Osmotically Regulated Delivery of Acyclovir

Table 4

Percent drug content, weight uniformity, and cumulative drug release data of the asymmetric membrane capsules of acyclovir.

Formulation codeWeight
(mg) ± S.D.
Drug content
(%) ± S.D.

(%) ± S.D.

F1697.60 ± 1.1897.74 ± 0.5570.07 ± 1.93
F2697.80 ± 1.0598.21 ± 0.6070.04 ± 1.36
F3697.95 ± 0.9998.36 ± 0.5491.16 ± 0.30
F4698.40 ± 0.7592.61 ± 1.4484.11 ± 0.95
F5769.10 ± 0.9194.63 ± 1.0880.59 ± 1.48
F6768.75 ± 1.0693.23 ± 1.3374.63 ± 0.46
F7769.35 ± 0.7499.45 ± 0.3797.88 ± 0.77
F8769.00 ± 1.0296.65 ± 1.5186.86 ± 1.25
F9732.95 ± 1.0997.12 ± 1.0895.20 ± 0.75

Average of 20 determinations; average of five determinations.
Extra design check point.