Combined Effect of Synthetic and Natural Polymers in Preparation of Cetirizine Hydrochloride Oral Disintegrating Tablets: Optimization by Central Composite Design

Figure 4

Response surface plot showing interaction of variable (concentration of CCS) and variable (concentration of HRM) influencing (a) disintegration time, (b) % friability, and (c) cumulative % drug release.

(a)

(b)

(c)