Combined Effect of Synthetic and Natural Polymers in Preparation of Cetirizine Hydrochloride Oral Disintegrating Tablets: Optimization by Central Composite Design
Table 1
Physicochemical parameters of mucilage powder (number of experiments = 3).
Parameters
Conditions
Angle of repose
26.37°
Bulk density
0.56 g/cm3
Tapped density
0.76 g/cm3
Average particle size
152 µm
Compressibility ratio
26.31
Loss on drying
5%
Percentage yield
29%
Swelling ratio
In water
48
Solubility
Slowly soluble in water producing huge viscous solution
