Combined Effect of Synthetic and Natural Polymers in Preparation of Cetirizine Hydrochloride Oral Disintegrating Tablets: Optimization by Central Composite Design

Table 8

Final optimized formulation () of CTZ ODTs formulation.

Composition	Amount
CTZ	10 mg
Pearlitol SD 100	128.91 mg
CCS	9.05 mg
HRM	16.04 mg
Sorbitol	20 mg
Other excipients	12 mg
Aspartame	4 mg

excipients: magnesium stearate: 2 mg, aerosil: 2 mg, talc: 2 mg, flavour: 6 mg, total tablet weight: 200 mg, and batch size: 50 tablets.