Research Article

Association of PLGA Microspheres to Carrier Pellets by Fluid Bed Coating: A Novel Approach towards Improving the Flowability of Microparticles

Table 1

Experimental domain evaluated (IV-Optimal factorial design).

FactorLevels
-10+1

(A) Polymer typeKollicoat® Protect-Kollidon® VA64
(B) Polymer concentration (% w/v)1.02.55.0
(C) Coating suspension to pellets ratio (mL/g)1:12:13:1