Antidiarrheal and Antioxidant Activities of Methanol Extract of Bryophyllum pinnatum Leaf Harvested from South-Eastern Nigeria in Mice

Table 1

Effect of BPE and loperamide on castor oil induced diarrhea on mice.

Percentage (%) wet stool
Treatment	1 h	2 h	3 h	4 h
Distilled water 10 ml/kg	76.66 ± 2.35	81.38 ± 2.00	82.57 ± 2.27	84.62 ± 2.23
Loperamide 5 mg/kg	0.00 ± 0.00	40.00 ± 16.32	88.75 ± 3.39	90.00 ± 2.98
BPE 50 mg/kg	48.33 ± 9.06	63.54 ± 11.01	83.06 ± 2.01	83.61 ± 2.18
BPE 100 mg/kg	28.33 ± 9.77	50.00 ± 11.57	61.66 ± 8.48	72.14 ± 5.13
BPE 200 mg/kg	20.83 ± 10.75	61.11 ± 2.02	63.49 ± 2.89	62.50 ± 4.56

when compared with distilled water treated group. BPE = Bryophyllum pinnatum Extract.