Review Article
The Influence of MHC and Immunoglobulins A and E on Host Resistance to Gastrointestinal Nematodes in Sheep
Table 1
Summary of studies that have implicated the MHC in resistance to gastointestinal parasites.
| Species | Parasite species | Method | MHC association | Reference |
| Sheep (Ovis aries) | mixed | Microarray | DQB1, DRA, DQA1 | [18] | | H. contortus | Microarray | DMB | [19] | | mixed | Microarray | DQA1*Null, DQB1, DRA | [20] | | mixed | PCR analysis | DQA1*Null | [21] | | mixed | PCR/sequencing | DQA1*0101, DQA1*0402 | [20] | | mixed | PCR/sequencing | DRB1 | [22, 23] | | mixed | PCR | DRB microsatellite | [23] | | Teladorsagia circumcincta | PCR/sequencing | DRB1 | [24ā27] | | H. contortus | PCR/sequencing | DRB1, OMHC1 | [28] | | Teladorsagia circumcincta | Linkage | Class IIb region | [29] | | | | | | Sheep (Ovis canadensis) | n/a | Population analysis PCR/sequencing | DRB1 | [30] | | | | | | Mouse (Mus musculus) | S. venezuelensis | Knock out | Class II | [31] | | H. polygyrus | Linkage | Class II region | [32, 33] | | | | | | Striped mouse (Rhabdomys pumilio) | mixed | PCR/sequencing | DRB | [34] | Yellow necked mouse (Apodemus flavicollis) | mixed | PCR/sequencing | DRB | [35] | Gray mouse lemur (Microcebusmurinus) | mixed | PCR/sequencing | DRB | [36] |
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