Research Article
Inhibition of the Growth of Plasmodium falciparum in Culture by Stearylamine-Phosphatidylcholine Liposomes
Table 1
Effects of Various Liposomes on the Viability of Plasmodium falciparum in vitro.
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Cells with 1% parasitemia and 2% hematocrit in the presence of various concentrations of above mentioned liposomal formulations (6.5 μM–208 μM lipids) and free spermidine (34 μM–1102 μM) were treated for 42 h at 37°C (in between at 24 h, [3H] hypoxanthine was added). The cell-associated radioactivity was determined and inhibition of growth calculated by comparison with controls (without liposomes/spermidine). |