The Role of Vitamin D and Vitamin D Receptor in Immunity to Leishmania major Infection

Figure 2

Lesion size is reduced in CYP27B1KO mice. C57BL/6 WT (closed circles) and CYP27B1KO (open circles) mice were infected with 10⁵  L. major parasites and the resulting lesions were measured at the indicated time points. Mean ± SE is presented; 𝑛 = (8–17). (b) Infected ears were harvested at 4, 8, and 12 weeks after infection, and parasite load was determined by limiting dilution assay. Each point indicates parasite burden in one ear. One representative of two independent experiments is presented. ^∗𝑃≤0.05.

(a)

(b)