Research Article

Modeling the Effects of Relapse in the Transmission Dynamics of Malaria Parasites

Figure 3

Mass drug administration (MDA) strategy applied in regions where P. falciparum (red) and P. vivax (blue) are equally prevalent. The initial parasite prevalence is equal for both P. vivax and P. falciparum as highlighted in Figures 2(c) and 2(d) by V and F, respectively. Asymptomatic infections are treated at a constant rate so they, on average, last as long as a clinical case. The red solid and dashed lines display interventions with durations just below and above the deterministic elimination threshold, respectively, for P. falciparum. For P. vivax, the model indicates no deterministic elimination threshold. The blue solid line represents continuing the intervention for 18 years and then halting, under 𝑝 1 = 𝑝 2 = 0 . 2 5 . The blue and red dot-dashed lines represent uninterrupted 20-year MDA campaigns.
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