TY - JOUR
A2 - Lopes, Marcela F.
AU - Mendes Wanderley, Joao Luiz
AU - Costa, Jaqueline França
AU - Borges, Valéria Matos
AU - Barcinski, Marcello
PY - 2012
DA - 2012/02/02
TI - Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of
Phosphatidylserine as a Main Regulator
SP - 981686
VL - 2012
AB - Leishmania amazonensis parasites cause progressive disease in most inbred mouse strains and are associated with the development of diffuse cutaneous leishmaniasis in humans. The poor activation of an effective cellular response is correlated with the ability of these parasites to infect mononuclear phagocytic cells without triggering their activation or actively suppressing innate responses of these cells. Here we discuss the possible role of phosphatidylserine exposure by these parasites as a main regulator of the mechanism underlying subversion of the immune system at different steps during the infection.
SN - 2090-0023
UR - https://doi.org/10.1155/2012/981686
DO - 10.1155/2012/981686
JF - Journal of Parasitology Research
PB - Hindawi Publishing Corporation
KW -
ER -