Novel Arsenic Nanoparticles Are More Effective and Less Toxic than As (III) to Inhibit Extracellular and Intracellular Proliferation of Leishmania donovani
Table 2
(a) Inhibition of parasite infection (at 37°C for 24 hours). (b) Inhibition of parasite attachment (at 4°C for 4 hours).
(a)
Sets
Total number of macrophages
Numbers of infected macrophages
Numbers of internalized parasites inside the macrophages
Control
500
2 M As-NP
500
0.1 M As (III)
500
1.0 M As (III)
500
2 M As (III)
500
values for number of infected macrophages and internalized parasites are 0.001 which is statistically significant.
(b)
Sets
Total number of macrophages
Numbers of infected macrophages
Numbers of attached parasites in the surface of macrophages
Control
200
52#
68#
2 M As-NP
200
22#
23#
values for number of infected macrophages and attached parasites are 0.0014 which is statistically significant.