Antimalarial Efficacy and Toxicological Assessment of Extracts of Some Ghanaian Medicinal Plants
Table 3
In vitro antiplasmodial activity of plant extracts.
Extract
IC50 (μg ∕ mL)
FCB
W2
CAM06
Paspalum scrobiculatum
24.02 ± 0.68
6.61 ± 0.69
16.31 ± 16.31
Bidens pilosa
23.48 ± 5.21
4.60 ± 0.91
21.43 ± 5.99
Acridocarpus alternifolius
74.10 ± 1.86
36.47 ± 28.76
65.10 ± 7.23
Clappertonia ficifolia
4.43 ± 0.18
7.94 ± 1.36
6.56 ± 3.09
Mitragyna ciliata
22.63 ± 3.81
18.64 ±1.66
48.64 ± 2.27
Parinari congensis
12.50 ± 2.18
51.52 ± 2.17
45.09 ± 6.12
Monanthotaxis caffra
5.86 ± 2.76
18.94 ± 1.53
18.54 ± 0.89
Datura stramonium
13.29 ± 4.68
116.86 ± 1.20
46.09 ± 4.90
Faurea speciosa
14.83 ± 1.89
9.31 ± 1.02
6.95 ± 2.05
Syzygium guineense
14.94 ± 1.89
4.62 ± 1.14
5.54 ± 1.05
Croton penduliflorus Hutch
5.37 ± 0.18
14.03 ± 17.04
14.66 ± 2.02
Quinine
0.09 ± 0.005
0.12 ± 0.03
0.10 ± 0.05
Concentration of extract that kills 50% of Plasmodium falciparum. According to [16], high (μg/mL), promising (μg/mL), moderate (μg/mL), and inactive (μg/mL).
