Research Article
Antiplasmodial and Cytotoxic Activities of Extracts of Selected Medicinal Plants Used to Treat Malaria in Embu County, Kenya
Table 4
Selectivity indices (SI) of the selected plant part(s) assayed against CQ-sensitive (D6) and CQ-resistant (W2) strains of P. falciparum.
| | Plant (parts used) | | SI | | Solvent of extraction | D6 | W2 |
| | Terminalia brownii Fresen. (leaf) | H2O | 14.4 | 8.20 | | MEOH | 8.95 | 5.47 | | DCM | 3.4 | 2.96 | | Erythrina abyssinica Lam. Ex DC. (stem bark) | H2O | 7.08 | 6.74 | | MEOH | 5.98 | 6.54 | | DCM | 4.6 | 3.53 | | Schkuhria pinnata (Lam.) Kuntze (whole plant) | H2O | 19.78 | 22.38 | | MEOH | 4.62 | 2.98 | | DCM | 2.6 | 2.65 | | Zanthoxylum chalybeum Engl. (leaf) | H2O | 0.62 | 0.65 | | MEOH | 1.01 | 0.67 | | DCM | 3.23 | 2.98 | | Leonotis mollissima Gurke. (leaf) | H2O | 9.85 | 9.27 | | MEOH | 8.55 | 8.53 | | DCM | 8.48 | 8.17 | | Tithonia diversifolia (Hemsl.) A. Gray (fruit) | H2O | 17.15 | 15.66 | | MEOH | 13.06 | 12.92 | | DCM | 29.81 | 25.55 | | Tithonia diversifolia (Hemsl.) A. Gray (leaf) | H2O | 16.61 | 14.65 | | MEOH | 5.25 | 3.38 | | DCM | 2.20 | 2.62 | | Senna didymobotrya (Fresen.) Irwin & Barneby (pod) | H2O | 2.32 | 2.41 | | MEOH | 2.44 | 2.48 | | DCM | 2.08 | 2.44 | | Senna didymobotrya (Fresen.) Irwin & Barneby (leaf) | H2O | 3.04 | 3.17 | | MEOH | 3.03 | 2.94 | | DCM | 2.6 | 2.49 | | Carissa edulis (Forssk.) Vahl (leaf) | H2O | 11.2 | 9.82 | | MEOH | 10.4 | 9.33 | | DCM | 9.56 | 9.85 | | Sterculia africana (Lour.) Fiori (stem bark) | H2O | 7.98 | 7.60 | | MEOH | 9.65 | 8.61 | | DCM | 17.3 | 19.86 |
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DCM: dichloromethane; MEOH: methanol; H2O: water.
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