Research Article

The Transmission Disequilibrium/Heterogeneity Test with Parental-Genotype Reconstruction for Refined Genetic Mapping of Complex Diseases

Table 7

Simulated true type I error rates of the RC-TDT and of RC-TDH.

Sibship size
RC-TDT RC-TDH RC-TDT RC-TDH RC-TDT RC-TDH

30.04900.05020.00940.01000.00080.0010
40.04850.04990.00970.00990.00100.0010
60.05030.04970.01010.01000.00080.0010

Determined on the basis of the dominant model with (scenario 4 in Table 4).